Research

Leading the field in equine genomics research

Plusvital has an extensive research team led by Chief Science Officer, Professor Emmeline Hill. Our team of world-leading scientists has expertise in molecular biology, genomics, bioinformatics, computational biology, equine exercise physiology, veterinary science, statistics and nutrition.

Our research is ongoing and ensures the most accurate and informative tests for genetic performance potential. Members of our research team have published over 200 scientific papers and 9 book chapters. A selection of these papers can be read by clicking the links and entering your details below.

Plusvital currently have a close research relationship with University College Dublin, Ireland, with global links to elite breeders and trainers within the Thoroughbred industry. We combine state-of-the-art genomics technology with large numbers of top-class horses at various stages of training and competition. We have tested over 15,000 horses, and over 1,000 Black Type individuals. Our clients are based in over 35 countries, including all major racing jurisdictions.

Research Papers

The “Speed Gene” Effect Of Myostatin Arises In Thoroughbred Horses Due To A Promoter Proximal SINE Insertion

07 Nov 2018

The “Speed Gene” Effect Of Myostatin Arises In Thoroughbred Horses Due To A Promoter Proximal SINE Insertion The “Speed Gene” Effect Of Myostatin Arises In Thoroughbred Horses Due To A Promoter Proximal SINE Insertion: Thoroughbred horses are finely-tu... / Read more »

Genetic Contributions To Precocity Traits In Racing Thoroughbreds

14 Mar 2018

Genetic Contributions To Precocity Traits In Racing Thoroughbreds Genetic Contributions To Precocity Traits In Racing Thoroughbreds: A new scientific paper describing the genetic contributions to precocity traits in Thoroughbreds has been published in the jour... / Read more »

Skeletal Muscle Mitochondrial Bioenergetics And Associations With Myostatin Genotypes In The Thoroughbred Horse

05 Feb 2018

Skeletal Muscle Mitochondrial Bioenergetics And Associations With Myostatin Genotypes In The Thoroughbred Horse Skeletal Muscle Mitochondrial Bioenergetics And Associations With Myostatin Genotypes In The Thoroughbred Horse: Variation in the myostatin (MSTN)... / Read more »

History And Integrity Of Thoroughbred Dam Lines Revealed In Equine mtDNA Variation

31 Mar 2017

History And Integrity Of Thoroughbred Dam Lines Revealed In Equine mtDNA Variation. History And Integrity Of Thoroughbred Dam Lines Revealed In Equine mtDNA Variation: This paper marked the first application of genetic technologies towards a scientific underst... / Read more »

A Genome Scan For Positive Selection In Thoroughbred Horses

31 Mar 2017

A Genome Scan For Positive Selection In Thoroughbred Horses A Genome Scan For Positive Selection In Thoroughbred Horses: This study reports regions of the Thoroughbred horse genome that have been targets for selection during the 300-year development of the rac... / Read more »

Evidence For Biogeographic Patterning Of Mitochondrial DNA Sequences In Eastern Horse Populations

31 Mar 2017

Evidence For Biogeographic Patterning Of Mitochondrial DNA Sequences In Eastern Horse Populations Evidence For Biogeographic Patterning Of Mitochondrial DNA Sequences In Eastern Horse Populations: The origins of equine domestication are unclear, but from this ... / Read more »

Mitochondrial DNA Sequence Diversity In Extant Irish Horse Populations And In Ancient Horses

31 Mar 2017

Mitochondrial DNA Sequence Diversity In Extant Irish Horse Populations And In Ancient Horses Mitochondrial DNA Sequence Diversity In Extant Irish Horse Populations And In Ancient Horses: Mitochondrial DNA in Ireland’s three native horse populations (Irish Dr... / Read more »

Genome Sequence, Comparative Analysis And Population Genetics Of The Domestic Horse

31 Mar 2017

Genome Sequence, Comparative Analysis And Population Genetics Of The Domestic Horse (Equus Caballus) Genome Sequence, Comparative Analysis And Population Genetics Of The Domestic Horse: This manuscript describes the horse genome – the entire complement of ge... / Read more »

Transcriptional Adaptations Following Exercise In Thoroughbred Horse Skeletal Muscle Highlight Molecular Mechanisms That Lead To Muscle Hypertrophy

31 Mar 2017

Transcriptional Adaptations Following Exercise In Thoroughbred Horse Skeletal Muscle Highlight Molecular Mechanisms That Lead To Muscle Hypertrophy Transcriptional Adaptations Following Exercise In Thoroughbred Horse Skeletal Muscle Highlight Molecular Mechani... / Read more »

A Sequence Polymorphism In MSTN Predicts Sprinting Ability And Racing Stamina In Thoroughbred Horses

31 Mar 2017

A Sequence Polymorphism In MSTN Predicts Sprinting Ability And Racing Stamina In Thoroughbred Horses A Sequence Polymorphism In MSTN Predicts Sprinting Ability And Racing Stamina In Thoroughbred Horses: This study describes the discovery of myostatin as the Sp... / Read more »

Alterations In Oxidative Gene Expression In Equine Skeletal Muscle Following Exercise And Training

31 Mar 2017

Alterations In Oxidative Gene Expression In Equine Skeletal Muscle Following Exercise And Training Alterations In Oxidative Gene Expression In Equine Skeletal Muscle Following Exercise And Training: The molecular adaptation to exercise was studied through anal... / Read more »

Characterization Of The Equine Skeletal Muscle Transcriptome Identifies Novel Functional Responses To Exercise Training

31 Mar 2017

Equine Skeletal Muscle Transcriptome Identifies Novel Functional Responses To Exercise Training Equine Skeletal Muscle Transcriptome Identifies Novel Functional Responses To Exercise Training: Exercise training in the Thoroughbred racehorse results in co-ordin... / Read more »

The Cosmopolitan Maternal Heritage Of The Thoroughbred Racehorse Breed Shows A Significant Contribution From British And Irish Mares

31 Mar 2017

The Cosmopolitan Maternal Heritage Of The Thoroughbred Racehorse Breed Shows A Significant Contribution From British And Irish Mares The Cosmopolitan Maternal Heritage Of The Thoroughbred Racehorse Breed Shows A Significant Contribution From British And Irish ... / Read more »

A Genome-Wide SNP-Association Study Confirms A Sequence Variant (g.66493737C>T) In The Equine Myostatin (MSTN) Gene As The Most Powerful Predictor Of Optimum Racing Distance For Thoroughbred Racehorses

31 Mar 2017

A Genome-Wide SNP-Association Study Confirms A Sequence Variant (g.66493737CT) In The Equine Myostatin (MSTN) Gene As The Most Powerful Predictor Of Optimum Racing Distance For Thoroughbred Racehorses A Genome-Wide SNP-Association Study Confirms A Sequence Var... / Read more »

Moderate And High Intensity Sprint Exercise Induce Differential Responses In COX4I2 And PDK4 Gene Expression In Thoroughbred Horse Skeletal Muscle

31 Mar 2017

Moderate And High Intensity Sprint Exercise Induce Differential Responses In COX4I2 And PDK4 Gene Expression In Thoroughbred Horse Skeletal Muscle Moderate And High Intensity Sprint Exercise Induce Differential Responses In COX4I2 And PDK4 Gene Expression In T... / Read more »

Association Of Sequence Variants In CKM And COX4I2 Genes With Racing Performance In Thoroughbred Horses

31 Mar 2017

Association Of Sequence Variants In CKM And COX4I2 Genes With Racing Performance In Thoroughbred Horses Association Of Sequence Variants In CKM And COX4I2 Genes With Racing Performance In Thoroughbred Horses: This study aimed to identify the relationship betwe... / Read more »

The Association Of Various Speed Indices To Training Responses In Thoroughbred Flat Racehorses Measured With A Global Positioning And Heart Rate Monitoring System

31 Mar 2017

The Association Of Various Speed Indices To Training Responses In Thoroughbred Flat Racehorses Measured With A Global Positioning And Heart Rate Monitoring System The Association Of Various Speed Indices To Training Responses In Thoroughbred Flat Racehorses Me... / Read more »

Circadian Regulation Of Locomotor Activity And Skeletal Muscle Gene Expression In The Horse

31 Mar 2017

Circadian Regulation Of Locomotor Activity And Skeletal Muscle Gene Expression In The Horse Circadian Regulation Of Locomotor Activity And Skeletal Muscle Gene Expression In The Horse: This study demonstrates that equine muscle function is influenced by circad... / Read more »

Targets Of Selection In The Thoroughbred Genome Contain Exercise-Relevant Gene SNPs Associated With Elite Racecourse Performance

31 Mar 2017

Targets Of Selection In The Thoroughbred Genome Contain Exercise-Relevant Gene SNPs Associated With Elite Racecourse Performance Targets Of Selection In The Thoroughbred Genome Contain Exercise-Relevant Gene SNPs Associated With Elite Racecourse Performance: T... / Read more »

Genome-Wide SNP Association-Based Localization Of A Dwarfism Gene In Friesian Dwarf Horses

31 Mar 2017

Genome-Wide SNP Association-Based Localization Of A Dwarfism Gene In Friesian Dwarf Horses Genome-Wide SNP Association-Based Localization Of A Dwarfism Gene In Friesian Dwarf Horses: The availability of the equine genome and commercial availability of an equin... / Read more »

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