Research

Leading the field in equine genomics research

Plusvital has an extensive research team led by Chief Science Officer, Professor Emmeline Hill. Our team of world-leading scientists has expertise in molecular biology, genomics, bioinformatics, computational biology, equine exercise physiology, veterinary science, statistics and nutrition.

Our research is ongoing and ensures the most accurate and informative tests for genetic performance potential. Members of our research team have published over 200 scientific papers and 9 book chapters. A selection of these papers can be read by clicking the links and entering your details below.

Plusvital currently have a close research relationship with University College Dublin, Ireland, with global links to elite breeders and trainers within the Thoroughbred industry. We combine state-of-the-art genomics technology with large numbers of top-class horses at various stages of training and competition. We have tested over 15,000 horses, and over 1,000 Black Type individuals. Our clients are based in over 35 countries, including all major racing jurisdictions.

Research Papers

Sequence Variants At The Myostatin Gene Locus Influence The Body Composition Of Thoroughbred Horses

31 Mar 2017

Sequence Variants At The Myostatin Gene Locus Influence The Body Composition Of Thoroughbred Horses Sequence Variants At The Myostatin Gene Locus Influence The Body Composition Of Thoroughbred Horses: This study examined the effect of myostatin genotype on bod... / Read more »

The Genetic Origin And History Of Speed In The Thoroughbred Racehorse

31 Mar 2017

The Genetic Origin And History Of Speed In The Thoroughbred Racehorse The Genetic Origin And History Of Speed In The Thoroughbred Racehorse: Selective breeding has resulted in an unusually high frequency of the C allele at the myostatin gene in Thoroughbred ho... / Read more »

A High Density SNP Array For The Domestic Horse And Extant Perissodactyla: Utility For Association Mapping, Genetic Diversity And Phylogeny Studies

31 Mar 2017

A High Density SNP Array For The Domestic Horse And Extant Perissodactyla: Utility For Association Mapping, Genetic Diversity And Phylogeny Studies A High Density SNP Array For The Domestic Horse And Extant Perissodactyla: Utility For Association Mapping, Gene... / Read more »

MSTN Genotype Association With Speed Indices In Thoroughbred Racehorses

31 Mar 2017

MSTN Genotype Association With Speed Indices In Thoroughbred Racehorses MSTN Genotype Association With Speed Indices In Thoroughbred Racehorses: This study examined the association of myostatin genotype with speed indices in Thoroughbred racehorses. Horses wit... / Read more »

A Cohort Study Of Racing Performance In Japanese Thoroughbred Racehorses Using Genome Information On ECA18

31 Mar 2017

A Cohort Study Of Racing Performance In Japanese Thoroughbred Racehorses Using Genome Information On ECA18 A Cohort Study Of Racing Performance In Japanese Thoroughbred Racehorses Using Genome Information On ECA18: Previous studies indicated that genotype at t... / Read more »

Truth In The Bones: Resolving The Identity Of The Founding Elite Thoroughbred Racehorses

31 Mar 2017

Truth In The Bones: Resolving The Identity Of The Founding Elite Thoroughbred Racehorses Truth In The Bones: Resolving The Identity Of The Founding Elite Thoroughbred Racehorses: This study examined whether the skeleton housed in the Royal Veterinary College, ... / Read more »

PGC-1α Encoded By The PPARGC1A Gene Regulates Oxidative Energy Metabolism In Equine Skeletal Muscle During Exercise

31 Mar 2017

PGC-1α Encoded By The PPARGC1A Gene Regulates Oxidative Energy Metabolism In Equine Skeletal Muscle During Exercise PGC-1α Encoded By The PPARGC1A Gene Regulates Oxidative Energy Metabolism In Equine Skeletal Muscle During Exercise: Peroxisome proliferator-a... / Read more »

MSTN Genotypes In Thoroughbred Horses Influence Skeletal Muscle Gene Expression And Racetrack Performance

31 Mar 2017

MSTN Genotypes In Thoroughbred Horses Influence Skeletal Muscle Gene Expression And Racetrack Performance MSTN Genotypes In Thoroughbred Horses Influence Skeletal Muscle Gene Expression And Racetrack Performance: This study demonstrates that myostatin may have... / Read more »

Genetic Diversity In The Modern Horse Illustrated From Genome-Wide SNP Data

31 Mar 2017

Genetic Diversity In The Modern Horse Illustrated From Genome-Wide SNP Data Genetic Diversity In The Modern Horse Illustrated From Genome-Wide SNP Data: This study is the first detailed description of equine breed diversity, using a genome-wide set of autosoma... / Read more »

Genome-Wide Analysis Reveals Selection For Important Traits In Domestic Horse Breeds

20 Feb 2017

Genome-Wide Analysis Reveals Selection For Important Traits In Domestic Horse Breeds Genome-Wide Analysis Reveals Selection For Important Traits In Domestic Horse Breeds: Selective breeding in horses focuses on preserving and improving traits related to aesthe... / Read more »

Mitochondrial DNA D-Loop Sequence Variation In Maternal Lineages Of Iranian Native Horses

20 Feb 2017

Mitochondrial DNA D-Loop Sequence Variation In Maternal Lineages Of Iranian Native Horses Mitochondrial DNA D-Loop Sequence Variation In Maternal Lineages Of Iranian Native Horses: Archaeological evidence indicates the presence of horses in Iran as early as 30... / Read more »

Thoroughbred Racehorse Mitochondrial DNA Demonstrates Closer Than Expected Links Between Maternal Genetic History And Pedigree Records

20 Feb 2017

Thoroughbred Racehorse Mitochondrial DNA Demonstrates Closer Than Expected Links Between Maternal Genetic History And Pedigree Records Thoroughbred Racehorse Mitochondrial DNA Demonstrates Closer Than Expected Links Between Maternal Genetic History And Pedigre... / Read more »

Genome-Wide Association Study Of Osteochondrosis In The Tarsocrural Joint Of Dutch Warmblood Horses Identifies Susceptibility Loci On Chromosomes 3 And 10

20 Feb 2017

Genome-Wide Association Study Of Osteochondrosis In The Tarsocrural Joint Of Dutch Warmblood Horses Identifies Susceptibility Loci On Chromosomes 3 And 10 Genome-Wide Association Study Of Osteochondrosis In The Tarsocrural Joint Of Dutch Warmblood Horses Ident... / Read more »

The Relationship Between Body Composition, Training And Race Performance In A Group Of Thoroughbred Flat Racehorses

20 Feb 2017

The Relationship Between Body Composition, Training And Race Performance In A Group Of Thoroughbred Flat Racehorses The Relationship Between Body Composition, Training And Race Performance In A Group Of Thoroughbred Flat Racehorses: Body composition is a non-i... / Read more »

Effect Of Training On PPARGC1A And FNDC5 Gene Expression In Thoroughbred Horses

20 Feb 2017

Effect Of Training On PPARGC1A And FNDC5 Gene Expression In Thoroughbred Horses Effect Of Training On PPARGC1A And FNDC5 Gene Expression In Thoroughbred Horses: PGC-1? and irisin, encoded by PPARGC1A and FNDC5 genes, play key roles in mediating the beneficial ... / Read more »

Candidate Gene SNP Associations With Fat-Free Mass (FFM) Measurements In Horses-In-Training

20 Feb 2017

Candidate Gene SNP Associations With Fat-Free Mass (FFM) Measurements In Horses-In-Training Candidate Gene SNP Associations With Fat-Free Mass (FFM) Measurements In Horses-In-Training: This study examined the effect of six candidate genes with functions in gro... / Read more »

Investigation Of MSTN Genotype Association With VO2peak In Untrained Yearlings

20 Feb 2017

Investigation Of MSTN Genotype Association With VO2peak In Untrained Yearlings Investigation Of MSTN Genotype Association With VO2peak In Untrained Yearlings: This study investigated the association between myostatin variations and VO2peak in 41 untrained year... / Read more »

A Single Nucleotide Polymorphism (BIEC2-808543) On ECA3 Is Associated With Recurrent Laryngeal Neuropathy Independent Of Height In Thoroughbred Horses

20 Feb 2017

A Single Nucleotide Polymorphism (BIEC2-808543) On ECA3 Is Associated With Recurrent Laryngeal Neuropathy Independent Of Height In Thoroughbred Horses A Single Nucleotide Polymorphism (BIEC2-808543) On ECA3 Is Associated With Recurrent Laryngeal Neuropathy Ind... / Read more »

Prehistoric Genomes Reveal The Genetic Foundation And Cost Of Horse Domestication

20 Feb 2017

Prehistoric Genomes Reveal The Genetic Foundation And Cost Of Horse Domestication Prehistoric Genomes Reveal The Genetic Foundation And Cost Of Horse Domestication: The genetics underlying horse domestication are difficult to reconstruct, given the near extinc... / Read more »

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